United States securities and exchange commission logo July 27, 2022 Ronald South Senior Vice President and Chief Financial Officer Henry Schein, Inc. 135 Duryea Road Melville, NY 11747 Re: Henry Schein, Inc. Form 10-K for the Fiscal Year Ended December 25, 2021 Filed February 15, 2022 File No. 000-27078 Dear Mr. South: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Office of Trade & Services